Dirk Görlich and Steven L. McKnight reveal new principles of intracellular transport and cellular organization——the 2025 Lasker Basic Medical Research Award

doi:10.3969/j.issn.1006-7795.2025.05.026

Abstract

Abstract: In 2025, The Lasker Award for Basic Medical Research were awarded to two scientists, Dirk Görlich and Steven L. McKnight, for their contributions to the structure and function of low-complexity domains (LCDs) in protein sequences. These discoveries reveal new principles of intracellular transport and cellular organization, overturning conventional knowledge and opening up novel horizons in the study of cellular transport and disease mechanisms.

Key words: The Lasker Award, low-complexity domains (LCDs), nuclear pore complex, nuclear transport, membrane-less organelle, neurodegenerative diseases

CLC Number:

Zhao Minghui, Shan Lin. Dirk Görlich and Steven L. McKnight reveal new principles of intracellular transport and cellular organization——the 2025 Lasker Basic Medical Research Award [J]. Journal of Capital Medical University, 2025, 46(5): 940-944.

References

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