Abstract: Objective  To investigate the clinical features of children with obstructive sleep apnea (OSA) and laryngopharyngeal reflux disease (LPRD). Methods  A cross-sectional study was performed on children who underwent polysomnogram (PSG) due to snoring in the Department of Otorhinolaryngology, Childrens Hospital of Capital Institute of Pediatrics from July 2024 to June 2025. The basic clinical data of the children were recorded, and the Pediatric Sleep Questionnaire-Sleep-Related Breathing Disorder Scale (PSQ-SRBD)， the Obstructive Sleep Apnea 18-Item Quality-Of-Life Questionnaire (OSA-18 ), Reflux Symptom Score (RSS), and Reflux Sign Assessment (RSA)were completed before polysomnography. The total RSS score>13 was the LPRD positive group, and the RSS total score ≤13 was the LPRD negative group, and the severity of OSA was graded according to the PSG monitoring results OAHI (obstructive apnea hypopnea index) ≤ 1 time/h was non-OSA, 1< OAHI ≤5 times/h was mild OSA, 5< OAHI ≤10 times/h was moderate OSA, 10< OAHI ≤30 times/h was severe OSA and OAHI>30 times/h was very severe OSA. Results  A total of 96 children with snoring were enrolled, including 62 males and 34 females, with a median age of 7 (5, 9) years. Among the 91 children with OSA, the positive rate of LPRD was 69.2% (63/91), and compared with the other groups, the RSS and RSA scores in the extremely heavy group were significantly higher (P<0.05). In addition, compared with the LPRD-negative group, the PSQ-SRBD, OSA-18 scores and OAHI scores of LPRD-positive children were significantly increased, and the minimum oxygen saturation was significantly decreased (P<0.05). Conclusion  The proportion of LPRD in children with OSA is higher, and the children with OSA are seriously affected by LPRD. Children with OSA and LPRD had specific manifestations in terms of symptoms and pharyngeal and laryngeal signs.

Key words: obstructive sleep apnea, laryngopharyngeal reflux, children, clinical characteristics, polysomnography monitoring, questionnaire