From molecular building blocks to the materials: metal-organic frameworks facilitate drug discovery——2025 Nobel Prize in Chemistry

doi:10.3969/j.issn.1006-7795.2025.06.026

Journal of Capital Medical University ›› 2025, Vol. 46 ›› Issue (6): 1157-1165.doi: 10.3969/j.issn.1006-7795.2025.06.026

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From molecular building blocks to the materials: metal-organic frameworks facilitate drug discovery——2025 Nobel Prize in Chemistry

Lu Tian, Zhang Jiyi, Ma Wenkuo, Wang Yuji ^*

Department of Medicinal Chemistry, School of Pharmaceutical Sciences, Capital Medical University； Engineering Research Center of Endogenous Prophylactic of Ministry of Education ； Beijing Major Laboratory of Peptide and Small Molecular Drugs, Beijing 100069, China

Received:2025-10-28 Revised:2025-10-30 Online:2025-12-21 Published:2025-12-19
Supported by:
This study was supported by Beijing Municipal Science & Technology Commission, Administrative Commission of Zhongguancun Science Park (Z241100009024044)， Beijing Under the CIMR Organized Scientific Research Program (CX23YZ06).

Abstract

Abstract: On October 8, 2025, Beijing time, The Royal Swedish Academy of Sciences announced that the 2025 Nobel Prize in Chemistry has been awarded to Susumu Kitagawa from Kyoto University, Japan; Richard Robson from University of Melbourne, Australia; and Omar M. Yaghi from University of California, Berkeley, USA. The award recognizes their pioneering contributions to the development of metal-organic frameworks (MOFs).

Key words: Nobel Prize in Chemistry, metal-organic frameworks, porous crystal materials, drug development, drug delivery, diagnosis and treatment integration

CLC Number:

Lu Tian, Zhang Jiyi, Ma Wenkuo, Wang Yuji . From molecular building blocks to the materials: metal-organic frameworks facilitate drug discovery——2025 Nobel Prize in Chemistry[J]. Journal of Capital Medical University, 2025, 46(6): 1157-1165.

References

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From molecular building blocks to the materials: metal-organic frameworks facilitate drug discovery——2025 Nobel Prize in Chemistry

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