Effect of Calcitonin Gene Related Peptide on the Arrhythmia Caused by Adenosine Diphosphate and Deacetyl-Lanatoside C in Rats

Abstract

Abstract: We investigated the effect of CGRP on the arrhythmia induced by two drugs in rats, The result of our experiment has proved that CGRP could reduce the degrees of A-V block, resist the attack of sinus stanstill and ventricular fibrillation produced by ADP, and improve restoration of sinus rhythm. CGRP could obviously eliminate sinus stanstill and ventricular fibrillation resulted from deacetyl-lanatoside C. These evidences demonstrate that CGRP is a peptide with a strong antiarrhythmic effect.

Key words: CGRP, arrhythmia, adenosine diphosphate (ADP), Deacetyl-Lanatoside C

Zhang Jianfeng;LiuJin;Sheng Shuli;Zhang Wanjiang. Effect of Calcitonin Gene Related Peptide on the Arrhythmia Caused by Adenosine Diphosphate and Deacetyl-Lanatoside C in Rats[J]. Journal of Capital Medical University, 1990, 11(4): 266-269.

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Effect of Calcitonin Gene Related Peptide on the Arrhythmia Caused by Adenosine Diphosphate and Deacetyl-Lanatoside C in Rats

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