Journal of Capital Medical University ›› 2001, Vol. 22 ›› Issue (1): 21-23.

• 论著 • Previous Articles     Next Articles

Effect of Different Constituents of Fetal Lamb on Adult Wound Healing

Wang Pengwen1, Yang Peisun1, Zhou Yijian Chen Jinjie1, Zhang Lianzhu2, Dong Rui'an2   

  1. 1. Department of Pathology, Capital University of Medical Sciences;2. Dept. of Surgery, Beijing Children's Hospital, Affiliate of Capital University of Medical Sciences
  • Received:2000-01-21 Revised:1900-01-01 Online:2001-01-15 Published:2001-01-15

Abstract: Different constituents of fetal lamb were used to induce scarless wound healing.Sheep wound models were prepared on both sides of vertebral column. Amniotic fluid, fetal skin and cord blood were picked up from pregnant sheep. Total protein amounts of different constituents were examined. Different constituents of fetal lamb were used to treat adult sheep wounds. To investigate the repair, compared the wound healing of 1 d, 3 d, 7 d and 14 d in the adult sheep during different treatments in HE and Masson staining. Electronic microscope observation was done in 7 d wounds. Results: During the same period, clean inflammation reaction, granulation tissue and collagen desposition are better in amniotic fluid group, fetal skin group and cord blood group than in Yunnan bai yao group and N.S group. But didn't find the scarless wound healing in those groups. Conclusion: The different constituents of fetal lamb may improve the wound repair in adult sheep and make wound healing in a shorter time.

Key words: fetal lamb, wound healing, special staining, electronic microscope

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