Abstract:

To determine the effects of urokinase and ticlopidine on blood viscosity parameters in the elderly patients. Fouty-six patients were randomly divided into two groups. Twenty-four patients were treated by vein with urokinase at dose of 250 000 U/d, 22 patients were treated with ticlopidine at dose of 0.25 g/d. And blood viscosity paramoters were measured. Both urokinase and ticlopidine could decrease blood viscosity, but have different effect on blood viscosity parameters. The two drugs have different effects on treating blood hyperviscosity. They should be used according to blood viscosity parameters.

Key words: urokinase, ticlopidine, hyperviscosity