Frequency Distribution of Apolipoprotein E Gene Polymorphism in Beijing Natural Population

Abstract

Abstract: The study was to determine apoEgene polymorphism by the technique of PCR-RFLP in Beijing nature population. The results show as follows: 1) The frequency of ε2、ε3、ε4 were 9.1%、81.2% and 9.7% respectively. There were not significant differences between male and female. 2) Compared with western countries and Japan, the frequency of ε2 increased while ε4 decreased in Beijing natural population. 3) The frequency of ε2 obviously increased in people with IFGand DM. 4) The frequency of ε2 decreases and ε4 increased in hypercholestesrolemia.

Key words: apolipoprotein E, gene, frequency

CLC Number:

Q513⁺.5

Li Xu;Zhao Dong;Liu Jing;Liu Sa;Liu Jun;Qin Lanping;Wu Zhaosu. Frequency Distribution of Apolipoprotein E Gene Polymorphism in Beijing Natural Population[J]. Journal of Capital Medical University, 2003, 24(3): 268-271.

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Frequency Distribution of Apolipoprotein E Gene Polymorphism in Beijing Natural Population

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