Changes of T cell and its Subgroup in Patients with Severe Acute Respiratory Syndrome

Journal of Capital Medical University ›› 2003, Vol. 24 ›› Issue (4): 392-395.

• 论著·临床研究 • Previous Articles Next Articles

Changes of T cell and its Subgroup in Patients with Severe Acute Respiratory Syndrome

Zhang Yonghong, Wu Hao, Chen Xinyue, Yan Huiping, Wen Tao, Tan Yufen, Ji Yunxia, Wu Yanning

Beijing Youan Hospital

Received:2003-07-17 Revised:1900-01-01 Online:2003-10-15 Published:2003-10-15

Abstract

Abstract: The objective was to observe the development and change of cell immunological function and analyze the cause.Prospective study was designed to analyze the development and changes of im-munological function in the following-up patients.Immunological function(CD₃⁺ ,CD₄⁺,CD₈⁺ )decreased most in the period of fastigium in SARS patient,and then recovered the the normal standard slowly on the60th days after onset.At the same time the ratio of CD₄⁺/CD₈⁺ was inverted in some patients of SARS.Different immunological functional damage(CD₃⁺ ,CD₄⁺,CD₈⁺)were found in differ-ent age groups(P<0.05).The change of immunological function are associated with the development of SARS,and the damage of immunological function is reversible.But we should pay attention to the phenomenon of inverting in the ratio of CD₄⁺/CD₈⁺.

Key words: severe acute respiratory syndrome(SARS), immunological function(CD₄⁺/CD₈⁺), follow-up

CLC Number:

R563.1

Zhang Yonghong;Wu Hao;Chen Xinyue;Yan Huiping;Wen Tao;Tan Yufen;Ji Yunxia;Wu Yanning. Changes of T cell and its Subgroup in Patients with Severe Acute Respiratory Syndrome[J]. Journal of Capital Medical University, 2003, 24(4): 392-395.

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Changes of T cell and its Subgroup in Patients with Severe Acute Respiratory Syndrome

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