Differential Expression of NDR2 mRNA in Hippocampus of Hypoxia Preconditioning Mice

Abstract

Abstract: The study was aimed to detect the chang of expression of NDR2 gene under hypoxia preconditioning. RT-PCR was used to examine the NDR2 gene responses to hypoxia exposure in mice hippocampus. Mice were divided into 3 groups randomly and were exposed to hypoxia for 4 runs(H4 group), 1 run(H1 group) and 0 run (control group). Total mRNA were extracted from mice hippocampus. The abundance of NDR2 mRNA was quantified. It was found that the level of NDR2 expression in hippocampus was increased significantly in group H1 and H4. These findings indicate that the NDR2 may play an important role in hypoxia and its preconditioning.

Key words: hypoxic preconditioning, hippocampus, NDR2, RT-PCR

CLC Number:

Q426

Shao Guo;Zhang Ran;Lü Guowei. Differential Expression of NDR2 mRNA in Hippocampus of Hypoxia Preconditioning Mice[J]. Journal of Capital Medical University, 2004, 25(2): 141-143.

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Differential Expression of NDR2 mRNA in Hippocampus of Hypoxia Preconditioning Mice

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