Abstract: Objective To investigate the features of the acute gastric mucosal lesion in patients with chronic severe-type hepatitis by endoscopy.Methods 521 patients were divided into three groups.Group A included 191 patients who were diagnosed as chronic severe-type hepatitis with underlying hepatocirrhosis,and group B including 175 patients with the same diagnosis as group A but underlain with chronic hepatitis,and group C,as control group,including 155 patients who were diagnosed as acute jaundiced hepatitis.All cases were examined with by endoscopy within 3 d after their being hospitalized.Results In Group A,there were 131 cases(68.6%) who was found the minifestations of portal hypertensive gastropathy(PHG),and acute gastric mucosal lesion(AGML) in 81 cases(42.4%),and in group B,PHG and AGML were found in 119 cases(68.0%)and 79 cases(45.1%),respectively.In group C,PHG and AGML were found in 11 cases(7.0%)and 21 cases(13.5%),respectively.There was no significant difference between the numbers of cases with PHG in group A and those in group B,so did the numbers of AGML.Compared with group C,there was significant difference in terms of either PHG or AGML in group A,and so did in group B compared with group C.Conclusion PHG and AGML pravelence present frequently in patients with chronic severe-type hepatitis underlain with either hepatocirrhosis or chronic hepatitis,and the appearance rates of the two kinds of lesions were much greatly in patients with chronic severe-type hepatitis than patients with acute jaundiced hepatitis.The presence of PHG /AGML is related to chronic liver disease(CLD) probably.

Key words: chronic severe-type hepatitis, portalvein hypertensive gastropathy, acute gastric mucosal lesion