Journal of Capital Medical University ›› 2007, Vol. 28 ›› Issue (2): 252-254.

• 临床研究 • Previous Articles     Next Articles

Study of Relationship between Hypertension in Patients with Tape-Ⅱ Diabetes Mellitus

Pan Yongyuan1, Li Jiaoyuan2, Wang Li1   

  1. 1. Department of Endocrinology, Xuanwu Hospital, Capital Medical University;2. Department of Endocrinology, Liaoyang Second People's Hospital
  • Received:2007-01-18 Revised:1900-01-01 Online:2007-04-24 Published:2007-04-24

Abstract: Objective To investigate the relationship between PAC-1 and hypertension in patients with tape-Ⅱ diabetes mellitus(DM). Methods One hundred and twenty eight patients with DM(tape-Ⅱ) were divided into 2 groups: hypertension group(68 cases) and normal blood pressure group(60 cases). Flow-cytometry was used to detect the PAC-1 level, and therefore between the 2 groups was analysed. And the correlation between hypertension, hyperglycemia and PAC-1 was evaluated. Results The PAC-1 level in patients with DM cases was higher than that in control group. It was also markedly higher in patients with hypertension than that in normal blood pressure group. blood pressure and plasma glucose correlated positively with PAC-1. Conclusion Hyperglycemia as sell as hypertension are main factors resulting in a high PAC-1 level.

Key words: tape-Ⅱ diabetes mellitus, flow-cytometry, activated platelets, hypertension

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