Abstract: Objective To study the effects on improving quality of life(QOL) in adult patients with epilepsy by enhancing the standardization of diagnosis and treatment.Methods Eighty adult patients with epilepsy under nonstandard diagnosis and treatment,whose disease course was at least one year and seizure frequency more than four times a month were enrolled standardization with strict procedure of diagnosis and treatment was then adopted.After three months' standard AEDs treatment,the QOL for these patients were evaluated by quality of life in epilepsy inventory-31(QOLIE-31,Chinese version).Results All aspects of QOL for patients with uncontrolled seizures had been decreased,among which the values of worry about seizure and effects of medication were lowest.At the same time gender,education background,occupation,economic status and living condition also affected the overall QOL and various scales of QOL.After standard treatment overall QOL and all scales were significantly improved,meanwhile the influence of the above factors on QOL were largely eliminated or obviously diminished.Conclusion Enhancing the standardization of diagnosis and treatment was the key to controlling seizure and improving QOL in adult patients with epilepsy.

Key words: epilepsy, standardization, diagnosis, treatment, quality of life