Polysomnographic characteristics of obstructive sleep apnea syndrome complicated with rapid eye movement (REM) sleep behavior disorder

doi:10.3969/j.issn.1006-7795.2014.05.026

Journal of Capital Medical University ›› 2014, Vol. 35 ›› Issue (5): 653-656.doi: 10.3969/j.issn.1006-7795.2014.05.026

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Polysomnographic characteristics of obstructive sleep apnea syndrome complicated with rapid eye movement (REM) sleep behavior disorder

Chang Yi¹, Nie Xiuhong¹, Zhan Shuqin², Zhao Xin², Wu Siqi², Gu Zhuqin², Chen Biao^2,3

1. Department of Respiratory Medicine, Xuanwu Hospital, Capital Medical University, Beijing 100053, China;
2. Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China;
3. Parkinson Disease Center of Beijing Institutes for Brain Disorders and Beijing Key Laboratory on Parkinson's Disease, Beijing 100069, China

Received:2014-06-11 Online:2014-10-21 Published:2014-10-20

Abstract

Abstract:

Objective To explore the relationship between REM sleep behavior disorder(RBD) and obstructive sleep apnea syndrome(OSAS).Methods Totally 76 OSAS subjects defined by AHI apnea-hypopnea index>10/h were enrolled from sleep disease center of Xuanwu Hospital from 2012 to 2013(28 RBD-OSAS cases and 48 OSAS controls). All subjects were undergone by one night video-polysomnography(vPSG) and the sleep apnea related parameters were compared between the two groups. Results Compared to OSAS group, RBD-OSAS patients had lower AHI index and hypopnea index, more severity of oxygen desaturation(baseline SpO₂ and minimum SpO₂) and longer maximum hypopnea time and <90% O₂ saturation duration(P<0.05).Conclusion RBD is capable of protecting against OSAS by increasing EMG activity of upper airway muscle tone during both REM and NREM sleep in RBD with OSAS patients. This result may provide a new direction for the treatment of OSAS.

Key words: rapid eye movement sleep behavior disorder (RBD), obstructive sleep apnea syndrome (OSAS), polysomnography

CLC Number:

R338.63

Chang Yi, Nie Xiuhong, Zhan Shuqin, Zhao Xin, Wu Siqi, Gu Zhuqin, Chen Biao. Polysomnographic characteristics of obstructive sleep apnea syndrome complicated with rapid eye movement (REM) sleep behavior disorder[J]. Journal of Capital Medical University, 2014, 35(5): 653-656.

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URL: https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/10.3969/j.issn.1006-7795.2014.05.026

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Polysomnographic characteristics of obstructive sleep apnea syndrome complicated with rapid eye movement (REM) sleep behavior disorder

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