Abstract: Objective To investigate the incidence,the risk factors and prognosis of the hepatic stress injury in early stage after traumatic brain injury in adults.Methods Total 329 cases with traumatic brain injury admitted and treated in our department from January 2005 to September 2005 were analyzed retrospectively.Results Forty-nine patients were diagnosed hepatic stress injury(14.9%).There is no difference in age,sex,injury type and site,between Group HSI and the control group.The degree of injury(GCS) in HSI is significantly more severe than the control(P<0.001).The mortality in HSI is increased(P<0.05).Conclusion HSI may appear in early stage after traumatic brain injury.There is close correlation between HSI and the degree of injury.The prognosis is not good,the total mortality is 30.6%.HSI needs more attention and active treatment.

Key words: hepatic stress injury(HSI), traumatic brain injury(TBI)