Abstract: Objective To test and verify the disconnection theory in conduction aphasia with diffusion tensor imaging. Methods 5 conduction aphasia cases and 5 volunteers carried out handedness assessment of aphasia battery of China meanwhile 5 conduction aphasia cases were studied using oral fluent test. We studied theses case's arcuate fasciculus with diffusion tensor imaging. Results All of these cases were right handedness. DTI showed that the fibers arcuate fasciculus were damaged at different levels compared with control group. Conclusion The disconnection between Broca's area and Wernicke's area is one of mechanisms in conduction aphasia.

Key words: conduction aphasia, arcuate fasciculus, disconnection theory