Abstract: Objective To evaluate the clinical value of ¹⁸F-FDG DHTC comprehensive analysis in the qualitative diagnosis and differential diagnosis of space occupying lesions in lung.Methods One hundred and seventy-six patients with lung occupying lesions on the X-ray film were diagnosed by comprehensive analysis,according to the uptake of FDG and the value of T/NT in the affected area.All the results were verified with those of biopsy.Results The space occupying lesions showed markedly increased tracer uptake in 138 patients with values of T/NT 2.1～18.0.The analyses showed 132 patients with malignancy and 6 with benign tumors.Lung cancer was proved by biopsy in 129 patients and benign tumors in 9 cases.Comprehensive analyses of 38 cases showing mild uptake with the value of T/NT 1.0～1.85 showed 15 malignancy and 23 benign tumors.Confirmed by biopsy results,16 cases were malignant and 22 benign.The sensitivity,specificity and accuracy of the diagnosis by tracer uptake of lesion alone were 88.96%,70.97% and 85.80% respectively,while those of comprehensive analysis were 96.55%,77.42% and 93.18% respectively.Conclusion The sensitivity,specificity and accuracy of the qualitative and differential diagnosis in lung occupying lesion are improved by the ¹⁸F-FDG DHTC comprehensive analysis.

Key words: lung occupying lesion, lung cancer, tomography, emission-computed, deoxyglucose