Abstract: Objective To detect serum specific IgE in allergic diseases for clinical diagnosis and therapy. Methods The serum specific IgE and total IgE(sIgE) were detected by enzyme immunoassay in 2 230 patients. Results The dermatophagoides farinae(28.3%) and pteronyssinus(26.6%) were the most common allergen in 2 230 patients, followed by Artemisia(14.9%), cat hair dander(9%), beef and mutton(9%), cockroaches(8.3%), seafood(8.1%), fungi(6.6%), milk(6.1%), short ragweed(5.6%), peanuts, cashew nuts(4.6%), elm, sycamore, willow, cottonwood(3.8%), egg white(3.8%), soybeans(3.1%). The positive rate of total IgE was 46.9%. Conclusion The detection of serum specific IgE and total IgE can help to find the corresponding clinical allergy, and provide evidences for prevention, diagnosis and therapy of allergic diseases.

Key words: allergic diseases, allergens, immunoglobulin E