Analysis of Relationship between High-sensitivity C-reactive Protein and Carotid Atherosclerosis in Hypertensive Patients

Journal of Capital Medical University ›› 2010, Vol. 31 ›› Issue (2): 268-271.

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Analysis of Relationship between High-sensitivity C-reactive Protein and Carotid Atherosclerosis in Hypertensive Patients

LI Jing-wei^*, DU Feng-he, XU Xiu-ying

Department of Cardiology, Beijing Tiantan Hospital, Capital Medical University

Received:1900-01-01 Revised:1900-01-01 Online:2010-04-21 Published:2010-04-21
Contact: LI Jing-wei

Abstract

Abstract:

Objective To study the relationship between serum high-sensitivity C-reactive protein(hsCRP) level and carotid atherosclerosis in elderly patients with essential hypertension. Methods The serum concentrations of high-sensitivity C-reactive protein(hsCRP) were measured in ninety-five elderly patients with essential hypertension. A color doppler ultrasound system was used to investigate the intimal-medial thickness(IMT) of common carotid artery(CCA) and the plaque of carotid artery. Results Serum hsCRP was significantly higher in the group with carotid atherosclerosis(CA) than in the group without CA〔(5.42±5.53) vs (2.78±3.22)mg/L, P=0.007〕. Conclusion Serum high-sensitivity C-reactive protein level is associated with carotid atherosclerosis in elderly patients with essential hypertension. Inflammatory response might play an important role in the pathogenesis of carotid atherosclerosis in patients with essential hypertension.

Key words: hypertension, carotid artery diseases, high sensitivity C reactive protein

CLC Number:

R 543.4

LI Jing-wei;DU Feng-he;XU Xiu-ying. Analysis of Relationship between High-sensitivity C-reactive Protein and Carotid Atherosclerosis in Hypertensive Patients[J]. Journal of Capital Medical University, 2010, 31(2): 268-271.

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Analysis of Relationship between High-sensitivity C-reactive Protein and Carotid Atherosclerosis in Hypertensive Patients

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