Journal of Capital Medical University ›› 1999, Vol. 20 ›› Issue (3): 156-158.

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Effect of Newcastle Disease Virus Losota 4 on BT325 Multicellular Spheroids

Li Aihua1, Pan Lizhen2, Ma Hongru2   

  1. 1. Department of Biochemistry, Capital University of Medical Sciences;2. Laboratory Center, Capital University of Medical Sciences
  • Received:1998-09-25 Revised:1900-01-01 Online:1999-07-15 Published:1999-07-15

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Abstract: The cytotoxic effects of NDV vaccine Losota-4 on multicellular spheroids model of human glioblastoma multiform BT325 were investigated. The results indicated that the diameter of spheroid decreased in all NDV titer (P<0.01). Survival assay showed that NDV could effectively kill glioblastoma cell (P<0.01).

Key words: Newcastle disease virus, BT325 spheroid, inhibition action

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