Abstract: Objective In this study, the stability, the hemocompatibility and the implantation possibility of a left ventricular assist device were evaluated. Methods First, the left ventricular assist device drove distilled water at room temperature for 30 days, and its stability was tested by the observation of the rotation speed and the current of the motor. Second, under the condition of 5 L/min and 100 mmHg, the in vitro hemolysis performance was evaluated with fresh sheep blood on a mock circulation loop and the standard hemolysis index NIH were measured. Finally, the implantation possibility of the blood pump were evaluated by in vivo animal test. The analog blood pump was implanted in the experimental animals' heart chamber and its implantation possibility was validated by comparing the preoperative and the postoperative chest X-ray of the experimental animals. Results Neither stuck nor leakage happened during the 30 days experiment; experimental results showed good hemolysis performance of the blood pump, the NIH value of the blood pump was(0.008±0.002)g/100 L; the blood pump did not squeeze the heart and its surrounding organs in all experimental animals, and it can be easily implanted in the heart chamber. Conclusion The results showed that the implantable ventricular assist device has good stability, hemocompatibility and implantation possibility.

Key words: ventricular assist device, blood pump, hemolysis, implantation possibility