Protective effect and the related mechanisms of rhubarb on ischemic cerebrovascular disease

doi:10.3969/j.issn.1006-7795.2015.05.011

Abstract

Abstract: Cerebral ischemia is the main leading cause of death and adult disability. Early thrombolysis is the most effective way to contain cerebral ischemic injury, however, its narrow therapeutic window and association with an increased risk of intracranial hemorrhage limits its application. As a traditional Chinese herbal medicine, rhubarb has many kinds of biological activities, such as anti-inflammatory, anti-oxidant, and anti-apoptotic effects. This paper reviews the neuroprotective effect and the related mechanisms of rhubarb on ischemic cerebrovascular disease.

Key words: rhubarb, ischemic cerebrovascular disease, inflammatory, reactive oxygen species(ROS), apoptosis

CLC Number:

R743

Fang Yalan, Luo Yumin, Zhao Yongmei. Protective effect and the related mechanisms of rhubarb on ischemic cerebrovascular disease[J]. Journal of Capital Medical University, 2015, 36(5): 718-722.

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URL: https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/10.3969/j.issn.1006-7795.2015.05.011

https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/Y2015/V36/I5/718

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