Analysis of risk factors for prolonged postoperative ileus in patients undergoing major abdominal surgery

doi:10.3969/j.issn.1006-7795.2020.04.024

Abstract

Abstract: Objective To determine the incidence and risk factors of prolonged postoperative ileus (PPOI) after major abdominal surgery in our hospital. Methods From July 2016 to December 2017, 123 patients who underwent radical operation of open digestive tract tumor were enrolled in the general surgery department of Beijing Friendship Hospital, Capital Medical University. Patients with PPOI were set as the case group (13 cases), otherwise it was the control group (110 cases). Univariate and multivariate logistic regression models were used to analyze the risk factors of PPOI. Results Univariate analysis showed that body mass index (BMI) <18.5 kg/m² (χ²=6.824, P=0.009) and postoperative hypokalemia (χ²=3.872, P=0.049) were related to PPOI. Multivariate regression analysis showed that BMI <18.5 kg/m² was an independent risk factor for PPOI. Conclusion The risk factors of PPOI may include BMI <18.5 kg/m² and postoperative hypokalemia. According to the chi-square test and logistic regression analysis, BMI is an independent risk factor for PPOI. The patients will be more at risk of PPOI when BMI<18.5 kg/m².

Key words: prolonged postoperative ileus, abdominal surgery, diagnosis, risk factors

CLC Number:

R719

Zhang Jinghui, Jin Lan, Li Jun, Wu Guocong, Yang Yun, Yao Hongwei, Yang Yingchi, Zhang Zhongtao. Analysis of risk factors for prolonged postoperative ileus in patients undergoing major abdominal surgery[J]. Journal of Capital Medical University, 2020, 41(4): 636-640.

0
/ / Recommend

Add to citation manager EndNote|Reference Manager|ProCite|BibTeX|RefWorks

URL: https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/10.3969/j.issn.1006-7795.2020.04.024

https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/Y2020/V41/I4/636

References 13

[1]	Vather R, Trivedi S, Bissett I. Defining postoperative ileus:results of a systematic review and global survey[J]. J Gastrointest Surg, 2013, 17(5):962-972.
[2]	Wolthuis A M, Bislenghi G, Fieuws S, et al. Incidence of prolonged postoperative ileus after colorectal surgery:a systematic review and Meta-analysis[J]. Colorectal Dis, 2016, 18(1):1-9.
[3]	Mao H, Milne T G E, O'grady G, et al. Prolonged postoperative ileus significantly increases the cost of inpatient stay for patients undergoing elective colorectal surgery:results of a multivariate analysis of prospective data at a single institution[J]. Dis Colon Rectum, 2019, 42(5):631-637.
[4]	Bragg D, El-Sharkawy A M, Psaltis E, et al. Postoperative ileus:recent developments in pathophysiology and management[J]. Clin Nutr, 2015, 34(3):367-376.
[5]	Vather R, O'grady G, Bissett I P, et al. Postoperative ileus:mechanisms and future directions for research[J]. Clin Exp Pharmacol Physiol, 2014, 41(5):358-370.
[6]	Sugawara K, Kawaguchi Y, Nomura Y, et al. Perioperative factors predicting prolonged postoperative ileus after major abdominal surgery[J]. J Gastrointest Surg, 2018, 22(3):508-515.
[7]	王宁, 陈凛, 李明森, 等. 胃癌患者发生延迟性术后肠麻痹的危险因素分析[J]. 中华胃肠外科杂志, 2018, 21(5):551-555.
[8]	Fitz-Henry J. The ASA classification and peri-operative risk[J]. Ann R Coll Surg Engl, 2011, 93(3):185-187.
[9]	Morales C H, Escobar R M, Villegas M I, et al. Surgical site infection in abdominal trauma patients:risk prediction and performance of the NNIS and SENIC indexes[J]. Can J Surg, 2011, 54(1):17-24.
[10]	Murphy M M, Tevis S E, Kennedy G D. Independent risk factors for prolonged postoperative ileus development[J]. J Surg Res, 2016, 201(2):279-85.
[11]	孟一森, 苏杨, 范宇, 等. 根治性膀胱全切术后肠梗阻的危险因素分析(附740例报道)[J]. 北京大学学报:医学版, 2015, 47(4):628-633.
[12]	中国超重肥胖医学营养治疗专家共识编写委员会. 中国超重/肥胖医学营养治疗专家共识(2016年版)[J]. 中华糖尿病杂志, 2016, 8(9):525-540.
[13]	蒋聪, 杨浩, 陈伟, 等. 住院病人的营养不良风险筛查[J]. 肠外与肠内营养, 2016, 23(3):158-161.

[1]	Feng Ying, Shi Ke, Wang Xianbo. Establishment and validation of 2-year predictive scoring model for patients with liver cirrhosis complicated with superior mesenteric venous thrombosis [J]. Journal of Capital Medical University, 2023, 44(1): 107-114.
[2]	Wang Jianlei, Zhu Tian, Han Yu, Wang Yue, Wen Chunmiao, Wei Jia. Analysis of human papilloma virus genotypes distribution characteristics and risk factors of the recurrence in male patients with condyloma acuminatum [J]. Journal of Capital Medical University, 2023, 44(1): 148-153.
[3]	Luo Shiyu, Li Mei, Luo Sha, Wang Shuang, Zhang Juan, Li Meng, Nan Xiao, Xian Junfang. Application value of ¹⁸F-FDG PET/CT in differential diagnosis of choroidal melanoma and choroidal metastatic carcinoma [J]. Journal of Capital Medical University, 2022, 43(6): 867-872.
[4]	Gu Feng, Jiang Wei, Liu Yuhang, Zhai Huihong. Risk factors for incomplete resection and prolonged operative duration of endoscopic submucosal dissection for colorectal tumors [J]. Journal of Capital Medical University, 2022, 43(6): 959-965.
[5]	Zhao Weihao, Zhang Yani, Li Ke, Yao Tian, Jing Lanmei, Huo Yujia, Ma Xiaoqin, Wang Xin, Liu Jing, Ma Xiaotao, Fu Rongguo, Tian Lifang. Analysis of risk factors associated with bleeding events after ultrasound-guided percutaneous native renal biopsies [J]. Journal of Capital Medical University, 2022, 43(5): 694-699.
[6]	Zhang Jingtao, Wang Xinran, Han Binru, Qiang Ying, Liu Xueqi, Zhang Yi. Analysis of clinical characteristics and risk factors of arrhythmia after thoracoscopic pneumonectomy in elderly patients with lung cancer [J]. Journal of Capital Medical University, 2022, 43(4): 564-569.
[7]	Tan Xiaogang, Zhang Yi. Clinical application of electromagnetic navigation bronchoscopy in the diagnosis and treatment of peripheral lung lesions [J]. Journal of Capital Medical University, 2022, 43(4): 570-575.
[8]	Gao Man, Li Haiyan. Application research hotspot of traditional Chinese medicine informatics [J]. Journal of Capital Medical University, 2022, 43(4): 592-599.
[9]	Tian Ming, Kong Qiu, Hou Xiaoxiao, Miao Jinwei. Clinicopathological analysis of benign and malignant struma ovarii [J]. Journal of Capital Medical University, 2022, 43(3): 343-349.
[10]	Hou Lei, Wang Xiaoxin, Liu Liheng, Zhang Weiyuan, Wang Xin. Chromosomal analysis in 134 cases of fetuses with growth restriction [J]. Journal of Capital Medical University, 2022, 43(3): 375-379.
[11]	Ren Chunqi, Kong Yu, Fu Shenggao, Zhu Zhengyan, Du Xin. Clinical characteristics and risk factors of young and middle-aged patients with calcified aortic valve disease [J]. Journal of Capital Medical University, 2022, 43(2): 187-191.
[12]	Wang Rongxin, Wang Jing, Hu Shuiqing. Analysis of risk factors in patients with reflux esophagitis with extra-esophageal symptoms [J]. Journal of Capital Medical University, 2022, 43(1): 132-137.
[13]	Lyu Han, Zhao Pengfei, Yin Hongxia, Wang Zhenchang. The innovation and application of key technologies in the otological radiology——The Second Prize of 2020 National Science and Technology Progress [J]. Journal of Capital Medical University, 2022, 43(1): 13-16.
[14]	Qi Zhili, Lin Jin, Dong Lei, Liu Jingfeng, Duan Meili. Meta-analysis of risk factors for bloodstream infections in intensive care unit [J]. Journal of Capital Medical University, 2021, 42(6): 923-930.
[15]	Gao Guangcheng, Sun Xin, Xu Ying, Zhuo Fenglin. Clinical analysis and experience summary of large vulvar ulcers in women [J]. Journal of Capital Medical University, 2021, 42(6): 1046-1052.