Clinical observation of autologous platelet rich fibrin in the treatment of refractory wounds

doi:10.3969/j.issn.1006-7795.2020.06.002

Journal of Capital Medical University ›› 2020, Vol. 41 ›› Issue (6): 876-881.doi: 10.3969/j.issn.1006-7795.2020.06.002

• Basic and Clinical Research on Plastic Surgery • Previous Articles Next Articles

Clinical observation of autologous platelet rich fibrin in the treatment of refractory wounds

Liu Jing¹, Wu Shunxiang¹, Han Yanfu¹, Xu Guang¹, Cui lei^1,2*

1. Department of Plastic Surgery, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China;
2. Department of Central Laboratory, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China

Received:2020-08-20 Online:2020-12-21 Published:2021-01-18
Contact: * E-mail: cuileite@aliyun.com
Supported by:
National Natural Science Foundation of China (81471798), Enhancement Funding of Laboratory of Center, Beijing Shijitan Hospital, Capital Medical University(2019-JS04).

Abstract

Abstract: Objective To observe the clinical efficacy of autologous platelet rich fibrin (PRF) in the treatment of chronic refractory wounds. Methods Totally 33 patients with chronic refractory wounds from March 2014 to March 2016were selected. After debridement, 33 patients were treated with PRF once a week. Taking wound healing as the index, the clinical efficacy was summarized. Results All 33 cases were treated with PRF 3 to 7 times, 21 cases of which were cured, 8 cases improved, and 4 cases ineffective. All patients were followed up for 3 to 6 months. No recurrence after wound healing. Conclusion The curative effect of autologous PRF in the treatment of refractory wound was explicit and definite. It could shorten the treatment course and reduce the cost, and no adverse reactions occurred during treatment. Therefore, it is a new simple and effective wound therapy technology.

Key words: refractory wounds, wound healing, platelet rich fibrin, clinical observation

CLC Number:

Liu Jing, Wu Shunxiang, Han Yanfu, Xu Guang, Cui lei. Clinical observation of autologous platelet rich fibrin in the treatment of refractory wounds[J]. Journal of Capital Medical University, 2020, 41(6): 876-881.

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Clinical observation of autologous platelet rich fibrin in the treatment of refractory wounds

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