Analysis of risk factors of cardiovascular disease in elderly hypertensive population in Tianjin community

doi:10.3969/j.issn.1006-7795.2021.05.017

Abstract

Abstract: Objective To predict the risk and trends of 10-year risk for cardiovascular diseases in elderly hypertensive population and to provide foundation data for the prevention and treatment of ischemic cardiovascular disease(ICVD). Methods Baseline data in 2016 and those of return visit in 2017 from 972 elderly hypertensive patients were collected and processed. Risk assessment and stratification of 10-year risk for cardiovascular disease(CVD) were conducted according to ICVD model. Results Compared with 2016, the absolute risk of 10-year risk of ICVD was much higher in 2017, raised from 12.8% to 16.8%(P＜0.01). In 2016, the proportion of the participants with high ICVD risk was raised from 59.3% to 67.7% (P＜0.01).Analysis on 154 patients with increased ICVD risk in this population revealed that body mass index (BMI), waist circumstance (WC), systolic blood pressure(SBP), blood glucose, blood lipids, blood urea nitrogen (BUN) and creatinine (Cr) were increased (P<0.01), the prevalence of overweight and obesity, hypercholesterolemia, hypertriglyceridemia, diabetes, metabolic syndrome, and impaired renal function were increased (P<0.01), suggesting that the increased 10-year risk of154 ICVD patients is related to the increase of these factors. Conclusion The level of cardiovascular disease risk factors in elderly hypertensive population in Tianjin community is relatively high, and is showing an upward trend. The risk of ICVD in the next 10 years is relatively high, and effective intervention should be strengthened according to risk factors.

Key words: hypertension, cardiovascular risk assessment, cardiovascular disease

CLC Number:

Liu Jin, Qi Xin, Qi Yanfang, Feng Jiaojiao, Peng Jinling. Analysis of risk factors of cardiovascular disease in elderly hypertensive population in Tianjin community[J]. Journal of Capital Medical University, 2021, 42(5): 804-809.

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URL: https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/10.3969/j.issn.1006-7795.2021.05.017

https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/Y2021/V42/I5/804

References

[1] Özerkan Cakan F. Hypertension in the elderly[J]. Turk Kardiyol Dern Ars, 2017, 45(Suppl 5): 29-31.
[2] Ferri C, Ferri L, Desideri G. Management of hypertension in the elderly and frail elderly[J]. High Blood Press Cardiovasc Prev, 2017, 24(1): 1-11.
[3] 国家“十五”攻关课题组.国人缺血性心血管病发病危险的评估方法及简易评估工具的开发研究[J]. 中华心血管病杂志,2003,31(12):893-901.
[4] Lewington S, Clarke R, Qizilbash N, et al. Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies[J]. Lancet, 2002, 360(9349): 1903-1913.
[5] Lawes C M, Rodgers A, Bennett D A, et al. Blood pressure and cardiovascular disease in the Asia Pacific region[J]. J Hypertens, 2003, 21(4): 707-716.
[6] 张秀芬.郝海水.老年高血压病患者血压与血脂和血糖以及脂肪肝的关系探究[J].实用心脑肺血管病杂志, 2007,27(S1): 122-124.
[7] 马里兰, 吴新华, 陈章荣,等. 云南农村地区50~74岁人群10年缺血性心血管病发病风险预测[J].中华高血压杂志[J]. 2015, 23(2): 178-181.
[8] 张纯燕,王冬,张慎和.2型糖尿病合并冠心病冠状动脉特点及危险因素分析[J].解放军医药杂志,2019,31(4):64-66.
[9] 吕赛,周玉杰,刘巍.高尿酸血症、代谢综合征与冠心病的研究进展[J].心肺血管病杂志,2018,37(1):76-78.
[10]Turin T C, James M T, Jun M, et al. Short-term change in eGFR and risk of cardiovascular events[J]. J Am Heart Assoc, 2014, 3(5): e000997.
[11]Rifkin D E, Shlipak M G, Katz R, et al. Rapid kidney function decline and mortality risk in older adults[J]. Arch Intern Med, 2008, 168(20): 2212-2218.
[12]Cheng T Y, Wen S F, Astor B C, et al. Mortality risks for all causes and cardiovascular diseases and reduced GFR in a middle-aged working population in Taiwan[J]. Am J Kidney Dis, 2008, 52(6): 1051-1060.

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