Journal of Capital Medical University ›› 2022, Vol. 43 ›› Issue (1): 1-5.doi: 10.3969/j.issn.1006-7795.2022.01.001

• Awards Introduction •     Next Articles

Research and application of a new technical system of hypoxic and ischemic conditioning for prevention and treatment of ischemic stroke——The Second Prize of 2020 National Science and Technology Progress

Zhao Wenbo, Ren Changhong, Li Sijie, Ma Hongrui, Ji Xunming*   

  1. Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China
  • Received:2021-12-01 Online:2022-02-21 Published:2022-01-27
  • Contact: * E-mail:jixm@ccmu.edu.cn

Abstract: Stroke is the first cause of death and disability in China, with high morbidity, recurrence, disability, mortality, and economic burden. Professor Ji Xunming et al. devoted themselves to exploring the prevention and treatment for stroke that would be suitable for Chinese population. They proposed theory of “hypoxic tissue conditioning” and verified the brain protection effect of hypoxic conditioning and elucidated the mechanism of its anti-ischemia and hypoxic injury. A new method of “limb remote ischemic adaptation” has been established to improve the efficacy of the prevention and treatment for ischemic stroke. The international guidelines and Chinese expert consensus on remote ischemic conditioning for the prevention and treatment of cerebrovascular diseases have been formulated and achieved.

Key words: cerebrovascular disease, ischemic stroke, hypoxic conditioning, remote ischemic conditioning, prevention

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