The value of combined superb microvascular imaging and color Doppler flow imaging in breast BI-RADS class 4 micronodules

doi:10.3969/j.issn.1006-7795.2023.06.003

Abstract

Abstract: Objective To investigate the role of superb microvascular imaging (SMI) and color Doppler flow imaging (CDFI) in the diagnosis of breast imaging reporting and data system (BI-RADS) type 4 micro nodules, and to compare it with contrast-enhanced ultrasound (CEUS). Methods A total of 165 patients was enrolled, with 165 breast micro nodules rated as BI-RADS class 4, with the maximum diameter ≤1 cm and confirmed by postoperative pathology. It included 125 benign lesions and 40 malignant lesions, and each lesion was examined by CDFI, SMI and CEUS, and the sonogram data were analyzed. Adler semi-quantitative method was used to evaluate blood flow grading, and CDFI and SMI showed the difference in blood flow in micro nodules. The diagnostic criteria for predicting the nature of nodules by CDFI, combined CDFI and SMI were developed, and the diagnostic value of CDFI, combined CDFI, SMI and CEUS in the nature of micro nodules in the breast was analyzed. Results Patients with malignant breast micro nodules were older than benign patients, and CDFI and SMI had different ability to detect breast micro nodules, and the CDFI blood flow rate was 47.3% (78/165) and SMI was 83.6% (138/165). Taking pathological results as the gold standard, the sensitivity of CDFI, combined CDFI, SMI and CEUS for the diagnosis of breast micro nodules is 72.5%, 87.5%, 72.5%, respectively, and the specificity is 60.8%, 59.2% and 82.4%, respectively. The accuracy was 63.6%, 66.1% and 80.0%, respectively, and the area under the curve(AUC)was 0.665, 0.771 and 0.772, respectively. The difference in the diagnosis of small nodules was statistically significant, so the combined application was better than CDFI alone. Conclusion For micro nodules of the breast diagnosed with BI-RADS class 4, the combined application of SMI techniques can help improve the sensitivity to determine the nature of nodules and reduce the use of ultrasonography for invasive examinations.

Key words: superb microvascular imaging, color Doppler flow imaging, contrast-enhanced ultrasound, micro tubercle of breast

CLC Number:

R445

Yu Tengfei, Yin Lu, Tian Daoran, Song Haiman, Yin Ziyi, Zhang Wei, He Wen . The value of combined superb microvascular imaging and color Doppler flow imaging in breast BI-RADS class 4 micronodules[J]. Journal of Capital Medical University, 2023, 44(6): 921-927.

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URL: https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/10.3969/j.issn.1006-7795.2023.06.003

https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/Y2023/V44/I6/921

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