Abstract: Objective To investigate the distribution and the drug-sensitivity of Candida SPP in the patients with uro-genital candidiasis in vitro in our hospital,and assess the clinical feasibility of to Candida Chromogenic & lsolation Medium.Methods 40 clinical strains from patients with uro-genital candidiasis in the dermatology department and the gynecology department in our hospital.Candida Chromogenic & lsolation Medium and microorganism automatic testing system were used to identify Candida species,and according to the NCCLS M-27A scheme with typical clinical symptoms,40 strains were studied,including 39 isolates from patients,1 quality control strain.Results 1) 37 of 40 isolates were candida albicans,2 of isolates were candida parapsilosis,and 1 of isolates was Cryptococcus laurentii.2) Drug sensitivity rate of yeast to amphotericin B,ketoconazole,miconazole,itraconazole,fluconazole,cytosine,terbinafine were 71.79%,100%,84.62%,41.03%,97.44%,97.44%,84.62% respectively.Conclusion 1) Among the clinical strains,Candida albicans was the most important pathomycete,and it had a high frequency in uro-genital candidiasis.2) indetification rate of Candida albicans was 100% with Candida Chromogenic & lsolation Medium coincides with microorganism automatic testing system.

Key words: genital candidosis, antifungal drug susceptibility microbial sensitivity tests, distribution of Candida SPP