感染新型冠状病毒患者的焦虑特质与心理健康的相关性研究

doi:10.3969/j.issn.1006-7795.2023.04.017

首都医科大学学报 ›› 2023, Vol. 44 ›› Issue (4): 609-613.doi: 10.3969/j.issn.1006-7795.2023.04.017

• 精神疾病中西医结合治疗 • 上一篇下一篇

感染新型冠状病毒患者的焦虑特质与心理健康的相关性研究

杨敬铭¹，王鑫²，刘丽改³，郝一炜⁴，宋蕊⁵，贾竑晓^6*

1.北京回龙观医院医务处，北京 100096；2.北京回龙观医院老年科，北京 100096；3.首都医科大学附属北京地坛医院肝病中心，北京 100015；4.首都医科大学附属北京地坛医院病案统计科，北京 100015；5.首都医科大学附属北京地坛医院感染科，北京 100015；6.首都医科大学附属北京安定医院国家精神心理疾病临床医学研究中心精神疾病诊断与治疗北京市重点实验室，北京 100088

收稿日期:2023-04-02 出版日期:2023-08-21 发布日期:2023-07-26
通讯作者: 贾竑晓 E-mail:jhxlj@vip.163.com
基金资助:
北京市市属医院科研培育计划项目（PX2018068）

Correlationship between anxiety trait and mental health in patients with severe acute respiratory syndrome coronavirus

Yang Jingming¹, Wang Xin², Liu Ligai³, Hao Yiwei⁴, Song Rui⁵，Jia Hongxiao^6*

1.Medical Section,Beijing Huilongguan Hospital, Beijing 100096, China；2.Department of Geriatrics, Beijing Huilongguan Hospital, Beijing 100096, China；3.Liver Disease Center, Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China；4.Department of Medical Records and Statistics, Beijing Ditan Hospital， Capital Medical University, Beijing 100015, China；5.Department of Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China；6.The National Clincal Research Center for Mental Disorders & Beijing Key Laboratory of Mental Disorders,Beijing Anding Hospital,Capital Medical University, Beijing 100088, China

Received:2023-04-02 Online:2023-08-21 Published:2023-07-26
Supported by:
This study was supported by the Beijing Municipal Hospital Scientific and Cultivate Project（PX2018068）.

摘要/Abstract

摘要： 目的探究感染新型冠状病毒（severe acute respiratory syndrome coronavirus 2， SARS-CoV-2）患者的焦虑特质与心理健康状态的关系，为目标人群心理症状的早期识别及早期干预提供依据。方法选取收治于首都医科大学附属北京地坛医院应急三病区和四病区确诊 SARS-CoV-2感染病例，轻型或普通型患者共72例，向所有患者发放特质焦虑问卷（Trait Anxiety Inventory，TAI），由精神科医师对完成自评问卷的患者进行面对面结构化访谈，使用汉密尔顿抑郁量表（Hamilton Depression Scale，HAMD）、汉密尔顿焦虑量表（Hamilton Anxiety Scale，HAMA）等他评工具对患者心理健康状态进行评估。结果伴焦虑/不伴焦虑的 SARS-CoV-2患者TAI评分差异有统计学意义（P<0.05）；伴抑郁/不伴抑郁的 SARS-CoV-2患者TAI评分差异有统计学意义（P<0.05）。经相关分析， SARS-CoV-2患者TAI评分与HAMA、HAMD总分存在显著相关（P<0.05）；具体而言， SARS-CoV-2患者的TAI评分与精神性焦虑、躯体性焦虑、焦虑/躯体化、认知症状、睡眠障碍、绝望感各因子分呈正相关。结论感染 SARS-CoV-2的患者焦虑抑郁的发生及严重程度与其特质焦虑水平的高低有关。

关键词: 新型冠状病毒, 焦虑特质, 心理健康

Abstract: Objective To explore the correlation between trait anxiety and mental health status of patients infected with severe acute respiratory syndrome coronavirus, and to provide evidences for early identification and early intervention of psychological symptoms in target population.Methods A total of 72 cases of mild or common patients diagnosed with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) were selected in two wards of the Beijing Ditan Hospital Capital Medical University. Trait Anxiety Inventory (TAI) was distributed to all patients. Psychiatrists conducted face-to-face structured interviews using Hamilton Depression Scale (HAMD) and Hamilton Anxiety Scale (HAMA) with patients who completed the self-assessment questionnaire to evaluate the mental health status. Results There was statistical significance in TAI scores difference between the SARS-CoV-2 patients with and without anxiety (P<0.05). The TAI scores difference between the SARS-CoV-2 patients with and without depression was also statistically significant (P<0.05).According to correlation analysis，the total scores of TAI significantly correlated with the total scores of HAMD and HAMA. Specifically, the TAI scores of SARS-CoV-2 patients were positively correlated with mental anxiety, somatic anxiety, anxiety/somatization, cognitive disturbance, sleep disturbance, and hopelessness.Conclusions The occurrence and severity of anxiety and depression in patients infected with SARS-CoV-2 are related to the level of trait anxiety.

Key words: severe acute respiratory syndrome coronavirus (SARS-CoV-2), anxiety trait, mental health

中图分类号:

杨敬铭, 王鑫, 刘丽改, 郝一炜, 宋蕊, 贾竑晓. 感染新型冠状病毒患者的焦虑特质与心理健康的相关性研究[J]. 首都医科大学学报, 2023, 44(4): 609-613.

Yang Jingming, Wang Xin, Liu Ligai, Hao Yiwei, Song Rui, Jia Hongxiao. Correlationship between anxiety trait and mental health in patients with severe acute respiratory syndrome coronavirus[J]. Journal of Capital Medical University, 2023, 44(4): 609-613.

参考文献

［1］ Xiang Y T, Yang Y, Li W, et al. Timely mental health care for the 2019 novel coronavirus outbreak is urgently needed［J］. Lancet Psychiatry, 2020, 7(3): 228-229.
［2］ Lima C K T, Carvalho P M D M, Lima I D A A S, et al. The emotional impact of Coronavirus 2019-nCoV (new Coronavirus disease)［J］. Psychiatry Res, 2020, 287: 112915.
［3］李伟, 张彩迪, 罗金晶, 等. 新型冠状病毒肺炎疫情期间不同人群心理状态的Meta分析［J］. 同济大学学报: 医学版, 2020, 41(2): 147-154.
［4］ Zhang H, Xie F, Yang B B, et al. Psychological experience of COVID-19 patients: a systematic review and qualitative meta-synthesis［J］. Am J Infect Control, 2022, 50(7): 809-819.
［5］ Yuan K, Zheng Y B, Wang Y J, et al. A systematic review and meta-analysis on prevalence of and risk factors associated with depression, anxiety and insomnia in infectious diseases, including COVID-19: a call to action［J］. Mol Psychiatry, 2022, 27(8): 3214-3222.
［6］ Lau J Y F, Eley T C, Stevenson J. Examining the state-trait anxiety relationship: a behavioural genetic approach［J］. J Abnorm Child Psychol, 2006, 34(1):19-27.
［7］刘岩, 张晓靖, 陈延飞. 假想和真实情景下特质焦虑对未来事件情绪预测的影响［J］. 中国心理卫生杂志, 2021, 35(5): 403-409.
［8］中华人民共和国国家卫生健康委员会办公厅,国家中医药管理局办公室.新型冠状病毒肺炎诊疗方案（试行第七版）［J］.中国医药,2020,15(6):801-805.
［9］汪向东, 王希林, 马弘. 心理卫生评定量表手册(增订版)［M］. 北京: 中国心理卫生杂志社, 1999: 205-209.
［10］ Moazen-Zadeh E, Bayanati S, Ziafat K, et al. Vortioxetine as adjunctive therapy to risperidone for treatment of patients with chronic schizophrenia: a randomised, double-blind, placebo-controlled clinical trial［J］. J Psychopharmacol, 2020, 34(5): 506-513.
［11］ Zimmerman M, Thompson J S, Diehl J M, et al. Is the DSM-5 anxious distress specifier interview a valid measure of anxiety in patients with generalized anxiety disorder: a comparison to the Hamilton Anxiety Scale［J］. Psychiatry Res, 2020, 286:112859.
［12］ Chen Y C, Liu J, Li Z X, et al. The tendency of modified electroconvulsive therapy-related working memory and subjective memory deficits in depression: a prospective follow-up study［J］. J ECT, 2020, 36(3): 198-204.
［13］ Zhang B, Cui C, Yu H X, et al. Association between ZNF184 and symptoms of Parkinson’s disease in southern Chinese［J］. Neurol Sci, 2020, 41(8): 2121-2126.
［14］ Wong M L, Anderson J, Knorr T, et al. Grit, anxiety, and stress in emergency physicians［J］. Am J Emerg Med, 2018, 36(6): 1036-1039.
［15］ Masiero M, Mazzocco K, Harnois C, et al. From individual to social trauma: sources of everyday trauma in Italy, the US and UK during the covid-19 pandemic［J］. J Trauma Dissociation, 2020, 21(5): 513-519.
［16］ Cho S, White K H, Yang Y, et al. The role of trait anxiety in the selection of emotion regulation strategies and subsequent effectiveness［J］. Pers Individ Dif, 2019, 147: 326-331.
［17］ Grupe D W, Nitschke J B. Uncertainty and anticipation in anxiety: an integrated neurobiological and psychological perspective［J］. Nat Rev Neurosci, 2013, 14(7): 488-501.
［18］ Bäuerle A, Teufel M, Musche V, et al. Increased generalized anxiety, depression and distress during the COVID-19 pandemic: a cross-sectional study in Germany［J］. J Public Health (Oxf), 2020, 42(4): 672-678.
［19］ Wang C Y, Pan R Y, Wan X Y, et al. Immediate psychological responses and associated factors during the initial stage of the 2019 coronavirus disease (COVID-19) epidemic among the general population in China［J］. Int J Environ Res Public Health, 2020, 17(5): 1729.
［20］于永菊. 焦虑和抑郁对正负性注意偏向的影响:注意控制的中介作用［J］. 心理与行为研究, 2020, 18(1): 121-127.
［21］ Stegmann Y, Reicherts P, Andreatta M, et al. The effect of trait anxiety on attentional mechanisms in combined context and cue conditioning and extinction learning［J］. Sci Rep, 2019, 9(1): 8855.
［22］刘溪, 梁宝勇, 高健, 等. 特质焦虑、应激和应对与心理健康的关系［J］. 中国健康心理学杂志, 2012, 20(4): 602-605.
［23］ Robinson E, Sutin A R, Daly M, et al. A systematic review and meta-analysis of longitudinal cohort studies comparing mental health before versus during the COVID-19 pandemic in 2020［J］. J Affect Disord, 2022, 296: 567-576.
［24］黄韩宇, 陈超, 司天梅. 新冠肺炎疑似患者的心理自助［J］. 中国心理卫生杂志, 2020, 34(3): 251-253.
［25］ Brebach R, Sharpe L, Costa D S J, et al. Psychological intervention targeting distress for cancer patients: a meta-analytic study investigating uptake and adherence［J］. Psychooncology, 2016, 25(8): 882-890.

[1]	刘亘梁, 于震维, 冯涛. 早发型帕金森病患者红细胞α-突触核蛋白水平及临床意义研究[J]. 首都医科大学学报, 2023, 44(5): 782-787.
[2]	霍园, 曲艳, 李晓红. 帕金森病冻结步态的非药物治疗的研究进展[J]. 首都医科大学学报, 2023, 44(5): 803-810.
[3]	胡正芳, 王娟, 菅敏钰, 韩如泉. 术中吸氧浓度对行脑血管再通术患者术后神经功能和并发症的影响[J]. 首都医科大学学报, 2023, 44(5): 865-871.
[4]	王荣亮, 闫峰, 田悦, 黄语悠, 罗玉敏, 马舒贝. 吡格列酮对小鼠脑缺血再灌注海马区神经元损伤的影响[J]. 首都医科大学学报, 2023, 44(4): 645-651.
[5]	李雪, 冯正田, 郑思思, 段宇航, 吴子遥, 朱虹, 贾竑晓. 广泛性焦虑障碍中医精神症状与躯体症状网络分析研究[J]. 首都医科大学学报, 2023, 44(4): 568-577.
[6]	郑思思, 宋明康, 宋楠, 朱虹, 贾竑晓. 度洛西汀治疗人格解体-现实解体障碍的探索性研究[J]. 首都医科大学学报, 2023, 44(4): 578-582.
[7]	宋明康, 徐天朝, 贾竑晓, 李冬冬, 郑思思, 尹冬青, 李雪. 基于聚类分析与贝叶斯网络的惊恐障碍中医证候规律探索[J]. 首都医科大学学报, 2023, 44(4): 583-589.
[8]	仲捷, 朱虹, 郝军, 贾竑晓. 心理理论能力在稳定期精神分裂症精神症状与社会功能之间的中介作用[J]. 首都医科大学学报, 2023, 44(4): 590-595.
[9]	仲捷, 朱虹, 郑思思, 贾竑晓. 基于机器学习的急性期精神分裂症心理理论能力对社会功能的预测作用[J]. 首都医科大学学报, 2023, 44(4): 596-601.
[10]	闫爱国, 刘鑫子, 尹冬青, 朱虹, 贾竑晓, 李自艳. 双相情感障碍复发相关的社会心理特征因素研究[J]. 首都医科大学学报, 2023, 44(4): 602-608.
[11]	王群松, 于海燕, 季向东, 李苗, 蒋怡烨. 电针对新型抗精神病药物所致代谢综合征的干预效果[J]. 首都医科大学学报, 2023, 44(4): 614-619.
[12]	赵惠卿, 张亚清. 全科医生偏头痛诊疗状况调查分析[J]. 首都医科大学学报, 2023, 44(3): 482-486.
[13]	胡舒缘, 张开元, 谷亚钦, 李京凯, 周陈, 吉训明, 段建钢. 糖皮质激素联合抗凝在急性/亚急性重症颅内静脉血栓治疗中的探索[J]. 首都医科大学学报, 2023, 44(2): 280-288.
[14]	梁发, 吴侑煊, 王鑫焱, 菅敏钰, 刘海洋, 韩如泉. 全身麻醉转化对急性脑卒中患者机械取栓术后神经功能的影响[J]. 首都医科大学学报, 0, (): 237-243.
[15]	李琼, 赵建华, 刘昊, 王凡, 李青, 陈希妍, 蔡瑞艳, 吴清武, 张健, 吉四辈, 路承彪, 李少敏. 脑白质高信号患者血清CX3CL1水平与认知功能障碍的关系[J]. 首都医科大学学报, 2023, 44(1): 6-12.

感染新型冠状病毒患者的焦虑特质与心理健康的相关性研究

Correlationship between anxiety trait and mental health in patients with severe acute respiratory syndrome coronavirus

PDF

可视化

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 15

编辑推荐

Metrics

本文评价