Journal of Capital Medical University ›› 2015, Vol. 36 ›› Issue (4): 573-577.doi: 10.3969/j.issn.1006-7795.2015.04.011

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Effect of uterine fibroids on fetal growths and neonatal outcomes in twin pregnancies

Wang Hongmei, Dai Yinmei, Tian Yucui, Xue Zhifang   

  1. Department of Gynecology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing 100026, China
  • Received:2015-05-22 Online:2015-08-21 Published:2015-07-17
  • Supported by:

    This study was supported by the Beijing Municipal Science&Technology Commission(Z131107002213090), Beijing Municipal Administration of Hospitals Clinical Medicine Development of Special Funding Support(ZYLX201510).

Abstract:

Objective To prospectively estimate the effect of fibroids on fetal growths and neonatal outcomes in twin pregnancies. Methods Data of 46 twin pregnancies with fibroids delivered from June 2013 to December 2014 in Beijing Obstetrics and Gynecology Hospital, Capital Medical University who have already established their records were collected. And data were also collected from 63 twin pregnancies without fibroids as matched group. The monitoring parameters of ultrasounds in their early, middle and late pregnancy and neonatal conditions and obstetric outcomes were observed and recorded. Results Twin pregnancies with fibroids were more likely to be of advanced maternal age 〔(35.04±4.24)years vs (31.67±3.56)years, P=0.000〕, higher pre-pregnancy body mass index 〔(21.46±3.69)kg/m2 vs (20.77±2.38)kg/m2, P=0.009〕 and had lower amniotic fluid volume〔(3.14±0.55)cm vs (3.38±0.55)cm, P=0.001〕 in 11-14 weeks ultrasound compared with twin pregnancies without fibroids. However, other parameters of fetal growths in early, middle and late pregnancy, neonatal conditions and obstetric outcomes had no statistical significance between twin pregnancies with fibroids and those without fibroids. Conclusion Fibroids' effect on fetal growths and neonatal outcomes in twin pregnancies is not obvious. But twin pregnancy is a high risk factor for pregnancy and we should give more monitoring and management for twin pregnancy with fibroids, so that mothers and newborns get more reasonable and secure treatment.

Key words: fibroids, twin pregnancy, growth, newborns

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