Journal of Capital Medical University ›› 2016, Vol. 37 ›› Issue (2): 219-222.doi: 10.3969/j.issn.1006-7795.2016.02.021

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Therapeutic effect of the decoction of Baihuxiaochi combined with promethazine in the treatment of tardive dyskinesias

Wang Lin1, Yuan Haining2, Jia Hongxiao2,3, Zhu Hong2, Kang Yuchun4   

  1. 1. Internist of the GuLou Hospital of Traditional Chinese Medicine of Beijing, Beijing 100089, China;
    2. The Fouth Ward of Beijing Anding Hospital, Capital Medical University, Beijing 100088, China;
    3. Beijing University of Chinese Medicine, Beijing 100029, China;
    4. Out-patient Department of Beijing Chaoyang Third Hospital, Beijing 100025, China
  • Received:2015-02-26 Online:2016-04-21 Published:2016-04-14
  • Supported by:
    This study was supported by Hebei Provincial Science and Technology Department Project(10276110D).

Abstract: Objective To observe the effect of the decoction of Baihuxiaochi combined with Promethazine in the treatment of tardive dyskinesias. Methods Totally 60 cases of tardive dyskinesias were divided into the control group or study group randomly. The control group was treated with Promethazine, while study group with Chinese medicine. The scores of Abnormal Involuntary Movement Scale(AIMS)and Positive and Negative Syndrome Scale(PANSS), Treatment Emergent Symptom Scale(TESS)were observed and compared.Results After treatment, the scores of AIMS in study group decreased significantly in contract with control group (P<0.01).The decrease of AIMS scores began in the fourth week and kept bigger till the end of study. While the scores of PANSS and TESS had not significantly changes at the ending point in contrast with contral group. Conclusion The decoction of Baihuxiaochi could treat the tardive dyskinesias.

Key words: tardive dyskinesias, Chinese medicine, the decoction of Baihuxiaochi, promethazine

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