Analysis of vestibular function and risk factors in pre-diabetic mellitus patients

doi:10.3969/j.issn.1006-7795.2019.01.003

Abstract

Abstract: Objective To compare the differences of vestibular function among the pre-diabetic patients and the controls and to analysis the characteristics and risk factors of vestibular dysfunction in pre-diabetic patients. Methods All participants underwent oral glucose tolerance test. Sixty-two pre-diabetic patients were enrolled with 44 age-and sex-matched controls. Weight, height, and other general information are collected in all subjects. Laboratory tests and vestibular caloric test were carried out. Slow phase velocity was collected. In pre-diabetic patients, the risk factors associated with vestibular dysfunction were analyzed. Results There were 44 cases with vestibular dysfunction in pre-diabetic patients, while 17 cases in the controls, with the statistically significant difference (P=0.001). Compared with the controls, slow phase velocity decreased in both eyes in the pre-diabetic patients, with the statistically significant difference (P=0.026 for the right eyes and P=0.016 for the left eyes). Logistic regression analysis showed that as age and glycosylated hemoglobin A1c (HbA1c) increased, the pre-diabetic patients had an increased risk of vestibular dysfunction (age P=0.013, HbA1c P=0.040). Conclusion The incidence of vestibular dysfunction is increased in the pre-diabetic patients. Age and HbA1c might be risk factors associated with vestibular dysfunction in the pre-diabetic patients.

Key words: pre-diabetic mellitus, vestibular dysfunction, caloric test

CLC Number:

R587.1

Meng Yan, Zhuang Xiaoming. Analysis of vestibular function and risk factors in pre-diabetic mellitus patients[J]. Journal of Capital Medical University, 2019, 40(1): 11-15.

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URL: https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/10.3969/j.issn.1006-7795.2019.01.003

https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/Y2019/V40/I1/11

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