Relationships between left ventricular myocardial mass index and PVC-burden and serum uric acid in patients with premature ventricular contractions

doi:10.3969/j.issn.1006-7795.2019.03.010

Abstract

Abstract: Objective To study the relationships between left ventricular myocardial mass index (LVMI) and PVC-burden and serum uric acid (UA) in patients with premature ventricular contractions(PVCs). Methods Totally 149 patients with PVCs were retrospectively analyzed. All the patients were divided into 2 groups with LVMI:the PVCs group (n=66) and the PVCs with left ventricular hypertrophy (LVH) group (n=83). The PVC-burden and UA level were compared and the Logistic regression analyses were used to identify the risk factors of LVH. Results Compared with the PVCs group, the PVC-burden and UA were increased in the PVCs with LVH group(P<0.05, respectively). In a binary Logistic regression analysis, age, PVC-burden and UA were the risk factors of LVH in patients with PVCs. Conclusion The LVMI was closely related to PVC-burden and UA. With the increase of PVCs burden, the patients with PVCs were prone to suffer LVH. For patients with a heavy load of PVC-burden and high level of UA, the cardiac function should be monitored on early stage and the clinical intervention should be provided in time.

Key words: premature ventricular complexes, left ventricular myocardial mass index, left ventricular hypertrophy

CLC Number:

R541.7

Luo Hongyu, Hua Qi, Liu Rongkun. Relationships between left ventricular myocardial mass index and PVC-burden and serum uric acid in patients with premature ventricular contractions[J]. Journal of Capital Medical University, 2019, 40(3): 374-378.

0
/ / Recommend

Add to citation manager EndNote|Reference Manager|ProCite|BibTeX|RefWorks

URL: https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/10.3969/j.issn.1006-7795.2019.03.010

https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/Y2019/V40/I3/374

References

[1] Simpson R J Jr, Cascio W E, Schreiner P J, et al. Prevalence of premature ventricular contractions in a population of African American and white men and women:the atherosclerosis risk in communities (ARIC) study[J]. Am Heart J, 2002, 143(3):535-540.
[2] Hasdemir C, Ulucan C, Yavuzgil O, et al. Tachycardia-induced cardiomyopathy in patients with idiopathic ventricular arrhythmias:the incidence, clinical and electrophysiologic characteristics, and the predictors[J]. J Cardiovasc Electrophysiol, 2011, 22(6):663-668.
[3] Ban J E, Kim Y H. PVC-induced cardiomyopathy:the cut-off value for the premature ventricular complex burden[J]. Europace, 2013, 15(7):1063-1064.
[4] Hasdemir C, Yuksel A, Camli D, et al. Late gadolinium enhancement CMR in patients with tachycardia-induced cardiomyopathy caused by idiopathic ventricular arrhythmias[J]. Pacing Clin Electrophysiol, 2012, 35(4):465-470.
[5] Duffee D F, Shen W K, Smith H C. Suppression of frequent premature ventricular contractions and improvement of left ventricular function in patients with presumed idiopathic dilated cardiomyopathy[J]. Mayo Clin Proc, 1998, 73(5):430-433.
[6] Dabbagh G S, Bogun F. Predictors and therapy of cardiomyopathy caused by frequent ventricular ectopy[J]. Curr Cardiol Rep, 2017, 19(9):80.
[7] Scridon A, Puertas R D, Manati W, et al. Age-dependent ventricular arrhythmias risk, structural and molecular remodeling in systemic arterial hypertension[J]. Mech Ageing Dev, 2017, 166:48-54.
[8] James M A, Jones J V. Systolic wall stress and ventricular arrhythmia:the role of acute change in blood pressure in the isolated working rat heart[J]. Clin Sci(Lond), 1990, 79(5):499-504.
[9] Priori S G, Blomström-Lundqvist C, Mazzanti A, et al. 2015 ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death:the task force for the management of patients with ventricular arrhythmias and the preventionof sudden cardiac death of the european society of cardiology (ESC)[J]. Eur Heart J, 2015, 36(41):2793-2867.
[10] Cuspidi C, Sala C, Negri F, et al. Prevalence of left-ventricular hypertrophy in hypertension:an updated review of echocardiographic studies[J]. J Hum Hypertens, 2012, 26(6):343-349.
[11] Verdecchia P, Carini G, Circo A, et al. Left ventricular mass and cardiovascular morbidity in essential hypertension:the MAVI study[J]. J Am Coll Cardiol, 2001, 38(7):1829-1835.
[12] Hlavá AčX ová M, Olejní AčX ková V, Ronzhina M, et al. Tolerance of isolated rabbit hearts to short ischemic periods is affected by increased LV mass fraction[J]. Physiol Res, 2017, 66(4):581-589.
[13] Rekhraj S, Gandy S J, Szwejkowski B R, et al. High-dose allopurinol reduces left ventricular mass in patients with ischemic heart disease[J]. J Am Coll Cardiol, 2013, 61(9):926-932.
[14] Kawamura M, Badhwar N, Vedantham V, et al. Coupling interval dispersion and body mass index are independent predictors of idiopathic premature ventricular complex-induced cardiomyopathy[J]. J Cardiovasc Electrophysiol, 2014, 25(7):756-762.
[15] Lelakowski J, Dreher A, Majewski J, et al. Effects of catheter ablation of idiopathic ventricular ectopic beats on left ventricular function and exercise capacity[J]. Kardiol Pol, 2009, 67(8):847-855.
[16] Dukes J W, Dewland T A, Vittinghoff E, et al. Ventricular ectopy as a predictor of heart failure and death[J]. J Am Coll Cardiol, 2015, 66(2):101-109.
[17] Algra A, Tijssen J G, Roelandt J R, et al. QT interval variables from 24 hour electrocardiography and the two year risk of sudden death[J]. Br Heart J, 1993, 70(1):43-48.
[18] Glatter K A, Myers R, Chiamvimonvat N. Recommendations regarding dietary intake and caffeine and alcohol consumption in patients with cardiac arrhythmias:what do you tell your patients to do or not to do?[J]. Curr Treat Options Cardiovasc Med, 2012, 14(5):529-535.
[19] Ribeiro W N, Yamada A T, Grupi C J, et al. Premature atrial and ventricular complexes in outpatients referred from a primary care facility[J]. PLoS One, 2018, 13(9):e0204246.
[20] Iwashima Y, Horio T, KamideK, et al. Uric acid, left ventricular mass index, and risk of cardiovascular disease in essential hypertension[J]. Hypertension, 2006, 47(2):195-202.
[21] Sachse A, Wolf G. Angiotensin Ⅱ-induced reactive oxygen species and the kidney[J]. J Am Soc Nephrol, 2007, 18(9):2439-2446.
[22] Zhong L, Lee Y H, Huang X M, et al. Relative efficacy of catheter ablation vs antiarrhythmicdrugs in treating premature ventricular contractions:a single-center retrospective study[J]. Heart Rhythm, 2014, 11(2):187-193.