Journal of Capital Medical University ›› 2023, Vol. 44 ›› Issue (2): 244-247.doi: 10.3969/j.issn.1006-7795.2023.02.010

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Analysis of risk factors of delirium and agitation during anesthesia emergence in pediatric neurosurgery patients

Wang Chengwei*, Yuan Linsong, Zhou Yang,Wang Huiwen   

  1. Department of Anaesthesiology,Beijing Tiantan Hospital,Capital Medical University, Beijing 100050, China
  • Received:2023-02-01 Online:2023-04-21 Published:2023-04-18
  • Supported by:
    This study was supported by Science and Technology Program of Beijing Municipal Commission of Science and Technology(Z19110700660000)

Abstract: Objective  To explore the risk factors of delirium and agitation in pediatric neurosurgery patients during anesthesia emergency. Methods  The clinical data of pediatric neurosurgery patients were retrospectively investigated with 120 cases  in the delirium and agitation group, and 392 cases  in the matched control group. Multivariate Logistic regression analysis was used to explore the risk factors of delirium and agitation in pediatric neurosurgery patients during anesthesia emergency. Results  Multivariate Logistic regression analysis showed that oral midazolam before operation (OR=2.695, 95% CI: 1.183-6.139, P=0.018), intraoperative infusion of dexmedetomidine (OR=0.210, 95% CI: 0.049-0.902, P=0.036) and combined inhalation anesthesia (OR=2.862, 95% CI: 1.300-6.301, P=0.009) were the risk factors of delirium and agitation in pediatric neurosurgery patients during anesthesia emergency. Conclusion  Oral midazolam before entering the operating room and combined inhalation anesthesia are independent risk factors for delirium and agitation, and dexmedetomidine can reduce the occurrence of delirium and agitation for pediatric neurosurgery patients.

Key words: pediatric neurosurgery patients, delirium and agitation, anesthesia emergency, risk factors

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