Journal of Capital Medical University ›› 1984, Vol. 5 ›› Issue (2): 134-142.

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Study on the Leucocyte Antigen System (HLA) of the Han Nationality Population in Beijing Area:Ⅱ.The Analysis and the Identification of Specificities of Lymphocytotoxicity Antisera

  

  • Received:1900-01-01 Revised:1900-01-01 Online:1984-04-15 Published:1984-04-15

Abstract: Establishing typing reagents of Chinese HLA,and standard HLA antisera,for filling some blanks in the medical scientific research is one of the problems of utmost importance.For this reasons a co-rrelative analysis was made on 261 strong by positive antisera which were screening out by using the micro lymphocyte cytotoxic test, with 83 international standard an-tisera including 44 specificities, and also with 39 known typing an-tigens assignment regions.Through analyses basing upon multiple cal-culation methods (clustering ana-lysis,includiug analysis,supple-mented clustering and including analysis,etc.)162 antisera of known types including 39 specifi-cities were obtained.Later on,the-se antisera of known types were identified again in two chessboa-rds.We selected 82 antisera inclu-ding 25 specificities which can be used as typing reagents.Except for those specificities with only one antiserum,these antisera had 18 compatibilities in order to deter-mine the antigens′ specificities.