Abstract:

In order to estimate the relationship between myocardial ischemia and dehydrogenase activity, the latter was tested with macroscopic enzymatic histochemical staining method in experimental myocardial ischemia of rabbits. The results showed that, if the ischemic condition laster more than one hour, the activity of dehydrogenase decreased in the in vivo specimen, whihile, in the in vitro specimen a prominent decrease of dehydrogenase activity did not occur until twenty-four hours. Besides, the relatively high activity in normal conditions conld last a longer time in lower temperature and disappeared rapidly as the ischemic myocardium was incubated in culture medium.