Abstract: A flame atomic absorption spectrometry method for the determination of micro-amounts beryllium in serum is described.The effect on the measurement from various elements in serum was studied.The Ca²⁺is a interference factor to the beryllium measurement.This factor can be dispelled by protein and other organic compounds in the serum. Sensitivity of this method is 0.026 μg/mL/0.1%,limitation of detection is 0.019μg/mL.

Key words: serum beryllium, deterrination of beryllium, atomic absorption spectrophotometry