Abstract: Proteins contained in the serum and subretinal fluid(SRF) from patients of retinal detachment with and without high myopia were analysed by vertical eletrophoresis using marker proteins. It was found that the serum proteins and their molecular weights in retinal detachment patients were essentially the same as those of the normal individual, the molecular weights being between 19.8×10～3u and 93.3×10～3u dalton in both cases But the contents and the molecular weight of the SRF protein increased as the course of the disease was prolonged, and in patients of over 2 months’ duration. Both these parameters became approximately the same as those of their own serum.

Key words: marker protcin, retinal detachment, subretinal fluid