Abstract: The present paper discusses the role of tremella fucitormis Polysaccharide(TFS) in pro-tection of erythrocyte membranes from damage by superoxide anion O₂^·- generated from auto-oxidation of pyrogallie acid(pA) at pH 8.4. The addition of TFS to pyrogallic acid and ery-thocyte membranes system caussed a decrease in high molecular weight protein polymers (HMP), an increase in fluidity and a depression in hemolysis rate of the red cells, Showing TFS has antiperoxidation effect on erythrocyte membranes. However no inhibition of TFS on auto-oxidative reaction of PA was shown when the auto-oxidation experiment was under taken under basic condition.

Key words: tremella fuciformis polysaccharide, erythrocyte membrane, superoxide anion, lipoperoxide