Journal of Capital Medical University ›› 1992, Vol. 13 ›› Issue (2): 124-127.

• 论著 • Previous Articles     Next Articles

Clinical Observation of Therapeutic Effect of Recombinant Human Erythropoietin in 25 Chronic Renal Insufficiency Patients

Chen Bingliang, Wu Yaojiong, Jia Qiang, Wei Shimin, Gao Guojing, Sun Yanbing, Yao Zheng   

  1. Department of Nephrdogy, Xuanmu Hospital, Capital Institute of Medicine
  • Received:1991-12-12 Revised:1900-01-01 Online:1992-04-15 Published:1992-04-15

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Abstract: 25 anemia patients caused by chronic renal insufficiency, 15 patients kept haemodialy-sis, the other received nondialysis treatment, were given recombinant human erythropoietin (r-HuEPO) thrice a week intravenously. Haemoglobin(Hb) rose to 106±8 g/L in 23 cases after 6～8 weeks accompanying increased life quality. 1 of 5 eases with low platelets counts and 1 of 3 cases with low leukocytes returned to normal 12 weeks after r-HuEPO adminis-tration. Mean WBC and platelets counts increased 12 weeks after r-HuEPO therapy. Mean blood pressure increased while haemoglobin rose. No significant changes were found in serum creatinine, uria, calcium, phosphorus, uric acid, cretinine clearance and 24h proteinurea amount.

Key words: anemia, r-HuEPO, chronic renal insufficiency

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