Journal of Capital Medical University ›› 1994, Vol. 15 ›› Issue (4): 261-264.

• 论著 • Previous Articles     Next Articles

In Vitro Effect of Ethanol Extract of Sophora Flavescens Ait on Giardia Lamblia

Wu Lingqing1, Lu Siqi2, Wang Fengyun2, Zhao Yuying3   

  1. 1. Department of Parasitology, College of Chinese Traditonal Medicine, Beijing Union University;2. Department of Parasitology, Capital Institute of Medicine;3. Department of Plant Chemistry,Pharmocology College, Beijing Medical University
  • Received:1993-08-26 Revised:1900-01-01 Online:1994-10-15 Published:1994-10-15

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Abstract: Ethanol extract of the Sophora flavecens Ait was evaluated in vitro for antigiardia effect.The lethal concentration to 99% of the organism was 5g/L on the 5h after cultivated with the trophozoites of Giardia lamblia. The lethality rates were decreased with the decline of the drug concentrations when cultivated with the parasites at the same period. The half lethal concentration was 1.5g/L and the shortest time at this concentration was 3h. The control test showed that 93.8% Giardia trophozites was killed by albendazole when it' s concentration was at 0.2g/L. The present study may provide an experimental datum for the treatment of giardiasis.

Key words: Giardia lamblia, ethanl extract of Sophora flavescens Ait, lethality rate, half lethal concentration

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