The Effect of Calcitonin Gene-Related Peptide on Reperfusion-Induced Arrhythmias in Rat

Abstract

Abstract: We investigated the effect of calcitonin gene-related peptide on the reperfusion-induced arrhythmias including ventricular tachycardia and fibrillation in the rat model of myocardial ischemia and reperfusion.The results demonstrated that calcitonin gene-related peptide(CGRP)obviously decreased and delayed the occurrence of ventricular tachycardia and fibrillation(P<0.01),shortened their duration of reperfusion-induced arrhythmias(P<0.05)and reduced mortality(P<0.05).

Key words: arrhythmias, calcitonin gene-related peptide(CGRP), rat

CLC Number:

R541.7

Zhang Jianfeng;Liu Jin;Liu Xuanzhong;Li Mingyue;Sheng Shuli;Zhang Wanjiang;Feng Rui'e;Zhu Chanren. The Effect of Calcitonin Gene-Related Peptide on Reperfusion-Induced Arrhythmias in Rat[J]. Journal of Capital Medical University, 1995, 16(2): 124-127.

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The Effect of Calcitonin Gene-Related Peptide on Reperfusion-Induced Arrhythmias in Rat

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