Journal of Capital Medical University ›› 1995, Vol. 16 ›› Issue (3): 189-193.

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Immunological Characteriotics of Lipopolysaccharide Core Region of Hafnia Alvei

An Yunqing, Appelmelk B J   

  1. 1. Department of Medical Microbiolegy and Immunology, Capital Institute of Medicine;2. Department of Medical Microbiology of Free University, The Netherlands
  • Received:1995-01-04 Revised:1900-01-01 Online:1995-07-15 Published:1995-07-15

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Abstract: Monoclonal antibodies(Mabs)and polyclonal antisera (Pabs) were used for characterizing the LP Score of 8 H.alvei strains :①Two anti-KDO Mabs (clone 14,20) detected α-linked KDO side chain in several(6, 5) but not all of the LPS. ②Mabs and Pabs specific for the R1～R4 core of E.coli did not react to the LPS core of H.alvei. ③The Mab (WN1222-5) specific for the Rc chemistry core of E.coli reacted strongly with all LPS of H.alvei tested. We conclude that the LPS of H.alvei contains both eiptopes (α-linked KDO side chain,Rc corel similar to those occurring in E.coli, but they are different in the core (R1～R4)types.

Key words: Hafnia alvei, lipopolysaccharide core (LPS core), monoclonal antibodies (Mabs)

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