Journal of Capital Medical University ›› 1997, Vol. 18 ›› Issue (3): 209-213.
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Pan Lizhen
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Abstract:
The cytotoxic effects of NDV(Losota-4)were investigated on multicellular spheriods of human lung adenocarcinoma A549.Spheriods of A549 were cultured at 37 ℃,5% CO2 for three days in various titers of NDVranging from 1/20,1/100 to 1/500 and then the diameters of sphriods were counted and cell proliferation from spheriods and their adhesion to culture surface were observed. The results indicated that the mean diameter of spheriods was decreased in all titers (P<0.05). Titers of NDVfrom 1/20 to 1/100 can inhibit cell proliferation from A549 spheriods and adhesion to culture surfaces.
Key words: Newcastle disease virus, human lung adenocarcinoma, multicellular spheriods
CLC Number:
R329.28
Pan Lizhen. Effects of Newcastle Disease Virus(Losota-4) on Human Lung Adenocarcinoma Cell Line A549 Multicellular Spheriods[J]. Journal of Capital Medical University, 1997, 18(3): 209-213.
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https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/Y1997/V18/I3/209
