Abstract: The distribution and number of dendritic cells in 60 cases of breast and tissue around the tumor were investigated. The result showed that S-100 protein positive dendritic cells distributed sparsely in malignant cells and formed a cluster among lymph cells and plasma cells.Such dendritic cell was related to histologic classification of breast carcinoma,metastases in lymph node and the intensity of lymphocyte and plasma cell infiltration around the carcinoma. This finding indicated that host antitumor immunoreaction that related to dendritic cells was different according to the phases of breast carcinoma.

Key words: breast carcinoma, S-100 protein, dedentric cells