Abstract:

Using MSG lesioned rats, the changes of enzymes and lipid in rat′s adrenal gland were studied . Animals were seperated into three groups of 11th day(newborn stage), 52th day(pu terty)and 100th day(adult). Each stage rats were seperated into two subgroups, the sham and lesion subgroups. The speciments of adrenal glands were stained with histochemistry and red oil O to show SDH,LDH,3-β-HSDH,G-6-Pase,G-6-PDH,NsE and lipid. Quantitative analyses were performed. The present study revealed that all of the above enzyme activities and lipid were elevated in lesion group of 11th day. In lesion group of 52th day and 100th day, the enzyme activities of LDH were elevated and other enzyme activities and lipid were low. These studies reveal that MSG may poisined on adrenal gland.

Key words: monosodium glutamate, histochemistry, adren gland, rat