Pathologic Studies of Placenta Due to Administration of Mifepristone and Misoprostol for Induction of Full-term Labor

Journal of Capital Medical University ›› 1998, Vol. 19 ›› Issue (2): 159-162.

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Pathologic Studies of Placenta Due to Administration of Mifepristone and Misoprostol for Induction of Full-term Labor

Gao Chunying¹, Liu Hui¹, Li Zhenqiang¹, Yu Wenhuan², Chen Ruifen³

1. Department of Pathology, Tiantan Hospital, Affiliate of Capital University of Medical Sciences;2. Department of Gynecology and Obstetric, Tiantan Hospital, Affiliate of Capital University of Medical Sciences

Received:1997-12-30 Revised:1900-01-01 Online:1998-04-15 Published:1998-04-15

Abstract

Abstract:

Pathologic changes of 22 cases of placenta due to administration of mifepristone and misoprostol for induction of full term labor were examined, 48 cases of normal full term placents were used as control group. Results: ①placental villus enlarged and decreased in number(P<0.01), ②the intervillus space narrowed(P<0.05), ③syncytial knot and syncytial sprout increased(P<0.01), ④capillary of the villus dilated and red blood cells in the capillary increased(P<0.01), ⑤electron microscope: microvillus shortened, decreased in number and disappeared, chromatin in the nucleus increased and condensed, rough endoplasm reticulum dilated, mitochondria swollened.

Key words: mifepristone, misoprostol, induction of labor, anoxia of placenta

CLC Number:

R719.31

Gao Chunying;Liu Hui;Li Zhenqiang;Yu Wenhuan;Chen Ruifen. Pathologic Studies of Placenta Due to Administration of Mifepristone and Misoprostol for Induction of Full-term Labor[J]. Journal of Capital Medical University, 1998, 19(2): 159-162.

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Pathologic Studies of Placenta Due to Administration of Mifepristone and Misoprostol for Induction of Full-term Labor

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