Journal of Capital Medical University ›› 1998, Vol. 19 ›› Issue (2): 166-167.

• 论著 • Previous Articles     Next Articles

The Effect of RU486 on Uterine Leiomyoma

Liu Fenzhe Ma Xiaorui1, Zhu Dingshou2, Xu Qing2, Liang Yuanjing2, Weng Jing2, Lu Xin2   

  1. 1. Department of Obstetrics and Genecology, Xuanwu Hospital, Affiliate of Capital University of Medical Sciences;2. Reproductive Medical Center, Capital University of Medical
  • Received:1997-07-11 Revised:1900-01-01 Online:1998-04-15 Published:1998-04-15

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Abstract: Eighteen patients with symptomatic leiomyoma were treated with 25 mg of RU486 daily for 3 months. All women were amenorrheic during the course of treatment. Leiomyoma volume decreased 36.9% after 3 moths′treatment. Compared with pretreatment values, RU486 treatment induced a decrease of serum P, but FSH, LH and E2 and remained unchanged. The study indicates that 25 mg of RU486 daily can induce a significant decrease in leiomyoma volume, and it may prove to be an assistant mode of treatment for uterine leiomyoma.

Key words: uterine leiomyoma, RU486, reproductive hormone

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