Investigation on Plasma Concentrations of ET-1 and CGRP in Sudden Deafness

Journal of Capital Medical University ›› 1998, Vol. 19 ›› Issue (2): 168-170.

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Investigation on Plasma Concentrations of ET-1 and CGRP in Sudden Deafness

Wang Xingyu¹, Kong Feng¹, Zhang Lirong¹, Li Zhongru Ai Houxi¹, Sheng Shuli²

1. Department of ENT, Xuanwu Hospital, Affiliate of Capital University of Medical Sciences;2. Polypepide Laboratory, Xuanwu Hospital, Affiliate of Capital University of Medical Scie

Received:1997-10-16 Revised:1900-01-01 Online:1998-04-15 Published:1998-04-15

Abstract

Abstract: In order to study the pathogenic mechanism of sudden deafness, the authors investigated and compared the plasma concentrations of ET-1 and CGRP in 24 cases of sudden deafness patients pre and post treatment. The result showsed: In the group in which hearing was clearly improved the concentration of ET-1 were significantly higher pre treatment than post treatment and the concentration of CGRP were much lower pre treatment than post treatment. The result indicated that high plasma concentration of ET-1 and low concentration of CGRP may act as the pathogenic factors predisposing occurrence of sudden deafness.

Key words: sudden deafness, ET-1, CGRP

CLC Number:

R764.437

Wang Xingyu;Kong Feng;Zhang Lirong;Li Zhongru Ai Houxi;Sheng Shuli. Investigation on Plasma Concentrations of ET-1 and CGRP in Sudden Deafness[J]. Journal of Capital Medical University, 1998, 19(2): 168-170.

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Investigation on Plasma Concentrations of ET-1 and CGRP in Sudden Deafness

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