Catechol-O-methyltransferase Gene Polymorphisms in Chinese Han Nationality

Journal of Capital Medical University ›› 2001, Vol. 22 ›› Issue (2): 113-115.

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Catechol-O-methyltransferase Gene Polymorphisms in Chinese Han Nationality

Gao Qingling, Shao Ming, Li Yongjie, Chen Biao

Xuanwu Hospital, Beijing Institute of Functional Neurosurgery, Affiliate of Capital University of Medical Sciences

Received:2000-05-16 Revised:1900-01-01 Online:2001-04-15 Published:2001-04-15

Abstract

Abstract: The polymorphism of G/A 1947 in exon 4 of COMT gene was analyzed in a population of 53 randomly selected Chinese individuals by polymerase chain reaction restriction fragment length polymorphism(PCR-RFLP). The frequency of A allele was 0.28. The index of homozygous G/G、G/A and A/A were 0.51, 0.42 and 0.07 respectively. The C1883/G and G1966/T polymorphism were found in a Chinese by genetic analyzer technique.

Key words: catechol-O-methyltransferase, gene, polymorphism, polymerase chain reaction

CLC Number:

Q786

Gao Qingling;Shao Ming;Li Yongjie;Chen Biao . Catechol-O-methyltransferase Gene Polymorphisms in Chinese Han Nationality[J]. Journal of Capital Medical University, 2001, 22(2): 113-115.

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Catechol-O-methyltransferase Gene Polymorphisms in Chinese Han Nationality

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