Abstract: The aim of this study is to investigate mechanisms of duodenal motility disorders presented in cold restraint stress rats by using electrode and highly sensitive sensor to record alterations of duodenum electromechanical activity. The study suggested that the average frequency and amplitude of duodenal slow wave was lower than the control group(P<0.001); Duodenal motion frequency of cold restraint stress rats was lower than that of the control groups(P<0.001), while motion amplitude was higher than that of the control groups. The time of MMC was obviously less than the control group. The results showed that changes of electro mechanical activity in duodenum of cold restraint stress rat and gastrointestinal peptides may be related to the gastrointestinal motility disorders presented in cold restraint stress rats.

Key words: cold restraint stress|duodenum|electro mechanical activity